Hul5 HECT Ubiquitin Ligase Plays A Major Role in The Ubiquitylation and Turn Over of Cytosolic Misfolded Proteins

Cellular toxicity introduced by protein misfolding threatens cell fitness and viability. Failure to eliminate these polypeptides is associated with numerous aggregation diseases. Several protein quality control mechanisms degrade non-native proteins by the ubiquitin proteasome system. Here, we use q...

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Detalles Bibliográficos
Autores principales: Fang, Nancy N., Ng, Alex H.M., Measday, Vivien, Mayor, Thibault
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961474/
https://www.ncbi.nlm.nih.gov/pubmed/21983566
http://dx.doi.org/10.1038/ncb2343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961474/
https://www.ncbi.nlm.nih.gov/pubmed/21983566
http://dx.doi.org/10.1038/ncb2343

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