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A genetically encoded bioluminescent indicator for illuminating proinflammatory cytokines

We introduce a method to evaluate the activities of cytokines based on the nuclear transport of NF-κB. A pair of bioluminescent indicators was made for conferring cytokine sensitivity to cervical carcinoma-derived HeLa cells. The principle is based on reconstitution of split fragments of Renilla ren...

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Detalles Bibliográficos
Autores principales: Kim, Sung Bae, Ozawa, Takeaki, Umezawa, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961787/
https://www.ncbi.nlm.nih.gov/pubmed/27489781
http://dx.doi.org/10.1016/j.mex.2016.06.001