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Data on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations
The t(12;21)(p13;q22), leading to ETV6/RUNX1 fusion, is of importance for leukemogenesis in acute lymphoblastic leukemia but is not sufficient for the leukemic transformation. Acquired secondary chromosomal aberrations are necessary for overt leukemia but their complete nature and genes involved are...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961797/ https://www.ncbi.nlm.nih.gov/pubmed/27508240 http://dx.doi.org/10.1016/j.dib.2016.06.060 |