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Hypoxia Associated Proteolytic Processing of OS-9 by the Metalloproteinase Meprin β

Meprin metalloproteases play a role in the pathology of ischemia/reperfusion- (IR-) induced renal injury. The endoplasmic reticulum-associated protein, osteosarcoma-9 (OS-9), has been shown to interact with the carboxyl-terminal tail of meprin β. More importantly, OS-9 interacts with the hypoxia ind...

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Detalles Bibliográficos
Autores principales: Martin, Barry Lee, Conley, Sabena Michelle, Harris, Regine Simone, Stanley, Corshe Devon, Niyitegeka, Jean-Marie Vianney, Ongeri, Elimelda Moige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961814/
https://www.ncbi.nlm.nih.gov/pubmed/27478637
http://dx.doi.org/10.1155/2016/2851803