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Phenotypes on demand via switchable target protein degradation in multicellular organisms

Phenotypes on-demand generated by controlling activation and accumulation of proteins of interest are invaluable tools to analyse and engineer biological processes. While temperature-sensitive alleles are frequently used as conditional mutants in microorganisms, they are usually difficult to identif...

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Detalles Bibliográficos
Autores principales: Faden, Frederik, Ramezani, Thomas, Mielke, Stefan, Almudi, Isabel, Nairz, Knud, Froehlich, Marceli S., Höckendorff, Jörg, Brandt, Wolfgang, Hoehenwarter, Wolfgang, Dohmen, R. Jürgen, Schnittger, Arp, Dissmeyer, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961840/
https://www.ncbi.nlm.nih.gov/pubmed/27447739
http://dx.doi.org/10.1038/ncomms12202