Magneto-nanosensor platform for probing low-affinity protein–protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction

Substantial efforts have been made to understand the interactions between immune checkpoint receptors and their ligands targeted in immunotherapies against cancer. To carefully characterize the complete network of interactions involved and the binding affinities between their extracellular domains,...

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Detalles Bibliográficos
Autores principales: Lee, Jung-Rok, Bechstein, Daniel J. B., Ooi, Chin Chun, Patel, Ashka, Gaster, Richard S., Ng, Elaine, Gonzalez, Lino C., Wang, Shan X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961847/
https://www.ncbi.nlm.nih.gov/pubmed/27447090
http://dx.doi.org/10.1038/ncomms12220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961847/
https://www.ncbi.nlm.nih.gov/pubmed/27447090
http://dx.doi.org/10.1038/ncomms12220

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