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Magneto-nanosensor platform for probing low-affinity protein–protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction
Substantial efforts have been made to understand the interactions between immune checkpoint receptors and their ligands targeted in immunotherapies against cancer. To carefully characterize the complete network of interactions involved and the binding affinities between their extracellular domains,...
Autores principales: | Lee, Jung-Rok, Bechstein, Daniel J. B., Ooi, Chin Chun, Patel, Ashka, Gaster, Richard S., Ng, Elaine, Gonzalez, Lino C., Wang, Shan X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961847/ https://www.ncbi.nlm.nih.gov/pubmed/27447090 http://dx.doi.org/10.1038/ncomms12220 |
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