Haplotyping the human leukocyte antigen system from single chromosomes

We describe a method for determining the parental HLA haplotypes of a single individual without recourse to conventional segregation genetics. Blood samples were cultured to identify and sort chromosome 6 by bivariate flow cytometry. Single chromosome 6 amplification products were confirmed with a s...

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Detalles Bibliográficos
Autores principales: Murphy, Nicholas M., Burton, Matthew, Powell, David R., Rossello, Fernando J., Cooper, Don, Chopra, Abha, Hsieh, Ming Je, Sayer, David C., Gordon, Lavinia, Pertile, Mark D, Tait, Brian D., Irving, Helen R., Pouton, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961964/
https://www.ncbi.nlm.nih.gov/pubmed/27461731
http://dx.doi.org/10.1038/srep30381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961964/
https://www.ncbi.nlm.nih.gov/pubmed/27461731
http://dx.doi.org/10.1038/srep30381

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