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Haplotyping the human leukocyte antigen system from single chromosomes
We describe a method for determining the parental HLA haplotypes of a single individual without recourse to conventional segregation genetics. Blood samples were cultured to identify and sort chromosome 6 by bivariate flow cytometry. Single chromosome 6 amplification products were confirmed with a s...
Autores principales: | Murphy, Nicholas M., Burton, Matthew, Powell, David R., Rossello, Fernando J., Cooper, Don, Chopra, Abha, Hsieh, Ming Je, Sayer, David C., Gordon, Lavinia, Pertile, Mark D, Tait, Brian D., Irving, Helen R., Pouton, Colin W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961964/ https://www.ncbi.nlm.nih.gov/pubmed/27461731 http://dx.doi.org/10.1038/srep30381 |
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