Stronger enhancer II/core promoter activities of hepatitis B virus isolates of B2 subgenotype than those of C2 subgenotype

Hepatitis B virus (HBV) genotype C causes prolonged chronic infection and increased risk for liver cancer than genotype B. Our previous work revealed lower replication capacity of wild-type genotype C2 than B2 isolates. HBV DNA replication is driven by pregenomic RNA, which is controlled by core pro...

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Detalles Bibliográficos
Autores principales: Qin, Yanli, Zhou, Xueshi, Jia, Haodi, Chen, Chaoyang, Zhao, Weifeng, Zhang, Jiming, Tong, Shuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961966/
https://www.ncbi.nlm.nih.gov/pubmed/27461034
http://dx.doi.org/10.1038/srep30374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961966/
https://www.ncbi.nlm.nih.gov/pubmed/27461034
http://dx.doi.org/10.1038/srep30374

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