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Stationary-Phase Mutagenesis in Stressed Bacillus subtilis Cells Operates by Mfd-Dependent Mutagenic Pathways

In replication-limited cells of Bacillus subtilis, Mfd is mutagenic at highly transcribed regions, even in the absence of bulky DNA lesions. However, the mechanism leading to increased mutagenesis through Mfd remains currently unknown. Here, we report that Mfd may promote mutagenesis in nutritionall...

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Detalles Bibliográficos
Autores principales: Gómez-Marroquín, Martha, Martin, Holly A., Pepper, Amber, Girard, Mary E., Kidman, Amanda A., Vallin, Carmen, Yasbin, Ronald E., Pedraza-Reyes, Mario, Robleto, Eduardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962003/
https://www.ncbi.nlm.nih.gov/pubmed/27399782
http://dx.doi.org/10.3390/genes7070033