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Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro

Guanidine alkaloids from sponges Monanchora spp. represent diverse bioactive compounds, however, the mechanisms underlying bioactivity are very poorly understood. Here, we report results of studies on cytotoxic action, the ability to inhibit EGF-induced neoplastic transformation, and the effects on...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Tabakmakher, Kseniya M., Hauschild, Jessica, Shchekaleva, Regina K., Otte, Katharina, Guzii, Alla G., Makarieva, Tatyana N., Kudryashova, Ekaterina K., Fedorov, Sergey N., Shubina, Larisa K., Bokemeyer, Carsten, Honecker, Friedemann, Stonik, Valentin A., von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962023/
https://www.ncbi.nlm.nih.gov/pubmed/27428983
http://dx.doi.org/10.3390/md14070133