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Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro
Guanidine alkaloids from sponges Monanchora spp. represent diverse bioactive compounds, however, the mechanisms underlying bioactivity are very poorly understood. Here, we report results of studies on cytotoxic action, the ability to inhibit EGF-induced neoplastic transformation, and the effects on...
Autores principales: | Dyshlovoy, Sergey A., Tabakmakher, Kseniya M., Hauschild, Jessica, Shchekaleva, Regina K., Otte, Katharina, Guzii, Alla G., Makarieva, Tatyana N., Kudryashova, Ekaterina K., Fedorov, Sergey N., Shubina, Larisa K., Bokemeyer, Carsten, Honecker, Friedemann, Stonik, Valentin A., von Amsberg, Gunhild |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962023/ https://www.ncbi.nlm.nih.gov/pubmed/27428983 http://dx.doi.org/10.3390/md14070133 |
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