Galangin Induces Autophagy via Deacetylation of LC3 by SIRT1 in HepG2 Cells

Galangin suppresses proliferation and induces apoptosis and autophagy in hepatocellular carcinoma (HCC) cells, but the precise mechanism is not clear. In this study, we demonstrated that galangin induced autophagy, enhanced the binding of SIRT1-LC3 and reduced the acetylation of endogenous LC3 in He...

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Detalles Bibliográficos
Autores principales: Li, Xv, Wang, Yajun, Xiong, Yuzhen, Wu, Jun, Ding, Hang, Chen, Xiaoyi, Lan, Liubo, Zhang, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962058/
https://www.ncbi.nlm.nih.gov/pubmed/27460655
http://dx.doi.org/10.1038/srep30496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962058/
https://www.ncbi.nlm.nih.gov/pubmed/27460655
http://dx.doi.org/10.1038/srep30496

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