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In silico synchronization reveals regulators of nuclear ruptures in lamin A/C deficient model cells

The nuclear lamina is a critical regulator of nuclear structure and function. Nuclei from laminopathy patient cells experience repetitive disruptions of the nuclear envelope, causing transient intermingling of nuclear and cytoplasmic components. The exact causes and consequences of these events are...

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Detalles Bibliográficos
Autores principales: Robijns, J., Molenberghs, F., Sieprath, T., Corne, T. D. J., Verschuuren, M., De Vos, W. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962089/
https://www.ncbi.nlm.nih.gov/pubmed/27461848
http://dx.doi.org/10.1038/srep30325