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In silico synchronization reveals regulators of nuclear ruptures in lamin A/C deficient model cells
The nuclear lamina is a critical regulator of nuclear structure and function. Nuclei from laminopathy patient cells experience repetitive disruptions of the nuclear envelope, causing transient intermingling of nuclear and cytoplasmic components. The exact causes and consequences of these events are...
Autores principales: | Robijns, J., Molenberghs, F., Sieprath, T., Corne, T. D. J., Verschuuren, M., De Vos, W. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962089/ https://www.ncbi.nlm.nih.gov/pubmed/27461848 http://dx.doi.org/10.1038/srep30325 |
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