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Mitochondrial DNA Damage and Diseases

Various endogenous and environmental factors can cause mitochondrial DNA (mtDNA) damage.  One of the reasons for enhanced mtDNA damage could be its proximity to the source of oxidants, and lack of histone-like protective proteins. Moreover, mitochondria contain inadequate DNA repair pathways, and, d...

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Detalles Bibliográficos
Autores principales: Singh, Gyanesh, Pachouri, U C, Khaidem, Devika Chanu, Kundu, Aman, Chopra, Chirag, Singh, Pushplata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962287/
https://www.ncbi.nlm.nih.gov/pubmed/27508052
http://dx.doi.org/10.12688/f1000research.6665.1