Antioxidant Protection of NADPH-Depleted Oligodendrocyte Precursor Cells Is Dependent on Supply of Reduced Glutathione

The pentose phosphate pathway is the main source of NADPH, which by reducing oxidized glutathione, contributes to antioxidant defenses. Although oxidative stress plays a major role in white matter injury, significance of NADPH for oligodendrocyte survival has not been yet investigated. It is reporte...

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Detalles Bibliográficos
Autores principales: Kilanczyk, Ewa, Saraswat Ohri, Sujata, Whittemore, Scott R., Hetman, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962338/
https://www.ncbi.nlm.nih.gov/pubmed/27449129
http://dx.doi.org/10.1177/1759091416660404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962338/
https://www.ncbi.nlm.nih.gov/pubmed/27449129
http://dx.doi.org/10.1177/1759091416660404

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