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Efficient TALEN-mediated myostatin gene editing in goats

BACKGROUND: Myostatin (MSTN) encodes a negative regulator of skeletal muscle mass that might have applications for promoting muscle growth in livestock. In this study, we aimed to test whether targeted MSTN editing, mediated by transcription activator-like effector nucleases (TALENs), is a viable ap...

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Detalles Bibliográficos
Autores principales: Yu, Baoli, Lu, Rui, Yuan, Yuguo, Zhang, Ting, Song, Shaozheng, Qi, Zhengqiang, Shao, Bin, Zhu, Mengmin, Mi, Fei, Cheng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962387/
https://www.ncbi.nlm.nih.gov/pubmed/27461387
http://dx.doi.org/10.1186/s12861-016-0126-9