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Placental transfer and mammary excretion of a novel angiotensin receptor blocker fimasartan in rats

BACKGROUND: Fimasartan (FMS) is a potent angiotensin receptor blocker for the treatment of mild to moderate hypertension. This study aimed to evaluate the transfer of FMS to fetus and breast milk in rats. METHODS: In order to study the transfer to the fetus and nursing pup, pregnant and nursing mate...

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Detalles Bibliográficos
Autores principales: Kim, Tae Hwan, Kim, Min Gi, Shin, Soyoung, Chi, Yong-Ha, Paik, Soo-Heui, Lee, Joo-Han, Yoo, Sun Dong, Youn, Yu Seok, Bulitta, Jürgen B., Joo, Sang Hoon, Jeong, Seok Won, Weon, Kwon-Yeon, Shin, Beom Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962410/
https://www.ncbi.nlm.nih.gov/pubmed/27459959
http://dx.doi.org/10.1186/s40360-016-0080-y