Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment

Tau, an intrinsically disordered protein confined to neuronal axons, binds to and regulates microtubule dynamics. Although there have been observations of string-like microtubule fascicles in the axon initial segment (AIS) and hexagonal bundles in neurite-like processes in non-neuronal cells overexp...

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Detalles Bibliográficos
Autores principales: Chung, Peter J., Song, Chaeyeon, Deek, Joanna, Miller, Herbert P., Li, Youli, Choi, Myung Chul, Wilson, Leslie, Feinstein, Stuart C., Safinya, Cyrus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962469/
https://www.ncbi.nlm.nih.gov/pubmed/27452526
http://dx.doi.org/10.1038/ncomms12278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962469/
https://www.ncbi.nlm.nih.gov/pubmed/27452526
http://dx.doi.org/10.1038/ncomms12278

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