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The Role of gsp Mutations on the Development of Adrenocortical Tumors and Adrenal Hyperplasia

Somatic GNAS point mutations, commonly known as gsp mutations, are involved in the pathogenesis of McCune–Albright syndrome (MAS) and have also been described in autonomous hormone-producing tumors, such as somatotropinoma, corticotrophoma, thyroid cancer, ovarian and testicular Leydig cell tumors,...

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Detalles Bibliográficos
Autores principales: Villares Fragoso, Maria Candida Barisson, Wanichi, Ingrid Quevedo, Cavalcante, Isadora Pontes, Mariani, Beatriz Marinho de Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962502/
https://www.ncbi.nlm.nih.gov/pubmed/27512387
http://dx.doi.org/10.3389/fendo.2016.00104