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The Role of gsp Mutations on the Development of Adrenocortical Tumors and Adrenal Hyperplasia
Somatic GNAS point mutations, commonly known as gsp mutations, are involved in the pathogenesis of McCune–Albright syndrome (MAS) and have also been described in autonomous hormone-producing tumors, such as somatotropinoma, corticotrophoma, thyroid cancer, ovarian and testicular Leydig cell tumors,...
Autores principales: | Villares Fragoso, Maria Candida Barisson, Wanichi, Ingrid Quevedo, Cavalcante, Isadora Pontes, Mariani, Beatriz Marinho de Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962502/ https://www.ncbi.nlm.nih.gov/pubmed/27512387 http://dx.doi.org/10.3389/fendo.2016.00104 |
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