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Complex relation of HLA-DRB1*1501, age at menarche, and age at multiple sclerosis onset

OBJECTIVE: To examine the relationship between 2 markers of early multiple sclerosis (MS) onset, 1 genetic (HLA-DRB1*1501) and 1 experiential (early menarche), in 2 cohorts. METHODS: We included 540 white women with MS or clinically isolated syndrome (N = 156 with genetic data available) and 1,390 w...

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Detalles Bibliográficos
Autores principales: Bove, Riley, Chua, Alicia S., Xia, Zongqi, Chibnik, Lori, De Jager, Philip L., Chitnis, Tanuja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962522/
https://www.ncbi.nlm.nih.gov/pubmed/27504495
http://dx.doi.org/10.1212/NXG.0000000000000088