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Complex relation of HLA-DRB1*1501, age at menarche, and age at multiple sclerosis onset
OBJECTIVE: To examine the relationship between 2 markers of early multiple sclerosis (MS) onset, 1 genetic (HLA-DRB1*1501) and 1 experiential (early menarche), in 2 cohorts. METHODS: We included 540 white women with MS or clinically isolated syndrome (N = 156 with genetic data available) and 1,390 w...
Autores principales: | Bove, Riley, Chua, Alicia S., Xia, Zongqi, Chibnik, Lori, De Jager, Philip L., Chitnis, Tanuja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962522/ https://www.ncbi.nlm.nih.gov/pubmed/27504495 http://dx.doi.org/10.1212/NXG.0000000000000088 |
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