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HIV integration and the establishment of latency in CCL19-treated resting CD4(+) T cells require activation of NF-κB

BACKGROUND: Eradication of HIV cannot be achieved with combination antiretroviral therapy (cART) because of the persistence of long-lived latently infected resting memory CD4(+) T cells. We previously reported that HIV latency could be established in resting CD4(+) T cells in the presence of the che...

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Detalles Bibliográficos
Autores principales: Saleh, Suha, Lu, Hao K., Evans, Vanessa, Harisson, David, Zhou, Jingling, Jaworowski, Anthony, Sallmann, Georgina, Cheong, Karey Y., Mota, Talia M., Tennakoon, Surekha, Angelovich, Thomas A., Anderson, Jenny, Harman, Andrew, Cunningham, Anthony, Gray, Lachlan, Churchill, Melissa, Mak, Johnson, Drummer, Heidi, Vatakis, Dimitrios N., Lewin, Sharon R., Cameron, Paul U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962537/
https://www.ncbi.nlm.nih.gov/pubmed/27459960
http://dx.doi.org/10.1186/s12977-016-0284-7