Changing of IKZF1 genotype during Philadelphia-negative precursor-B acute lymphoblastic leukemia progression: a short clinical report

• The case demonstrated a rare event of clonal heterogeneity by IKZF1 gene status in BCRABL1- ALL. • IKZF1 deletions are secondary events in ALL caused by clonal evolution during the treatment. • It's prognostic significance could be more crucial in BCR-ABL- rather than in BCR-ABL + ALL. • IKZF...

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Detalles Bibliográficos
Autores principales: Vshyukova, Volha, Meleshko, Alexander, Mihal, Natalia, Aleinikova, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962816/
https://www.ncbi.nlm.nih.gov/pubmed/27489764
http://dx.doi.org/10.1016/j.lrr.2016.06.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962816/
https://www.ncbi.nlm.nih.gov/pubmed/27489764
http://dx.doi.org/10.1016/j.lrr.2016.06.005

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