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Changing of IKZF1 genotype during Philadelphia-negative precursor-B acute lymphoblastic leukemia progression: a short clinical report
• The case demonstrated a rare event of clonal heterogeneity by IKZF1 gene status in BCRABL1- ALL. • IKZF1 deletions are secondary events in ALL caused by clonal evolution during the treatment. • It's prognostic significance could be more crucial in BCR-ABL- rather than in BCR-ABL + ALL. • IKZF...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962816/ https://www.ncbi.nlm.nih.gov/pubmed/27489764 http://dx.doi.org/10.1016/j.lrr.2016.06.005 |