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Cocaine Self-Administration Elevates GluN2B within dmPFC Mediating Heightened Cue-Elicited Operant Responding

Cue-elicited drug-craving correlates with hyperactivity within prefrontal cortex (PFC), which is theorized to result from dysregulated excitatory neurotransmission. The NMDA glutamate receptor is highly implicated in addiction-related neuroplasticity. As NMDA receptor function is regulated criticall...

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Detalles Bibliográficos
Autores principales: Szumlinski, Karen K, Wroten, Melissa G, Miller, Bailey W, Sacramento, Arianne D, Cohen, Matan, Ben-Shahar, Osnat, Kippin, Tod E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962921/
https://www.ncbi.nlm.nih.gov/pubmed/27478879