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PLGA particulate delivery systems for subunit vaccines: Linking particle properties to immunogenicity

Among the emerging subunit vaccines are recombinant protein- and synthetic peptide-based vaccine formulations. However, proteins and peptides have a low intrinsic immunogenicity. A common strategy to overcome this is to co-deliver (an) antigen(s) with (an) immune modulator(s) by co-encapsulating the...

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Detalles Bibliográficos
Autores principales: Silva, A. L., Soema, P. C., Slütter, B., Ossendorp, F., Jiskoot, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962933/
https://www.ncbi.nlm.nih.gov/pubmed/26752261
http://dx.doi.org/10.1080/21645515.2015.1117714