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Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging Gliomas

BACKGROUND: A critical challenge in the management of Glioblastoma Multiforme (GBM) tumors is the accurate diagnosis and assessment of tumor progression in a noninvasive manner. We have identified Membrane-type 1 matrix metalloproteinase (MT1-MMP) as an attractive biomarker for GBM imaging since thi...

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Detalles Bibliográficos
Autores principales: de Lucas, A. G., Schuhmacher, A. J., Oteo, M., Romero, E., Cámara, J. A., de Martino, A., Arroyo, A. G., Morcillo, M. Á., Squatrito, M., Martinez-Torrecuadrada, J. L., Mulero, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962974/
https://www.ncbi.nlm.nih.gov/pubmed/27462980
http://dx.doi.org/10.1371/journal.pone.0158634