Targeting Tumor Cells with Anti-CD44 Antibody Triggers Macrophage-Mediated Immune Modulatory Effects in a Cancer Xenograft Model

CD44, a transmembrane receptor reported to be involved in various cellular functions, is overexpressed in several cancer types and supposed to be involved in the initiation, progression and prognosis of these cancers. Since the sequence of events following the blockage of the CD44-HA interaction has...

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Detalles Bibliográficos
Autores principales: Maisel, Daniela, Birzele, Fabian, Voss, Edgar, Nopora, Adam, Bader, Sabine, Friess, Thomas, Goller, Bernhard, Laifenfeld, Daphna, Weigand, Stefan, Runza, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963023/
https://www.ncbi.nlm.nih.gov/pubmed/27463372
http://dx.doi.org/10.1371/journal.pone.0159716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963023/
https://www.ncbi.nlm.nih.gov/pubmed/27463372
http://dx.doi.org/10.1371/journal.pone.0159716

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