Cargando…

Inhibition of the Binding between RGS2 and β-Tubulin Interferes with Spindle Formation and Chromosome Segregation during Mouse Oocyte Maturation In Vitro

RGS2 is a negative regulator of G protein signaling that contains a GTPase-activating domain and a β-tubulin binding region. This study aimed to determine the localization and function of RGS2 during mouse oocyte maturation in vitro. Immunofluorescent staining revealed that RGS2 was widely expressed...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Man-Xi, Shi, Yan, Sun, Zhao-Gui, Zhang, Zhi, Zhu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963123/
https://www.ncbi.nlm.nih.gov/pubmed/27463806
http://dx.doi.org/10.1371/journal.pone.0159535