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Inhibition of the Binding between RGS2 and β-Tubulin Interferes with Spindle Formation and Chromosome Segregation during Mouse Oocyte Maturation In Vitro
RGS2 is a negative regulator of G protein signaling that contains a GTPase-activating domain and a β-tubulin binding region. This study aimed to determine the localization and function of RGS2 during mouse oocyte maturation in vitro. Immunofluorescent staining revealed that RGS2 was widely expressed...
Autores principales: | Jiang, Man-Xi, Shi, Yan, Sun, Zhao-Gui, Zhang, Zhi, Zhu, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963123/ https://www.ncbi.nlm.nih.gov/pubmed/27463806 http://dx.doi.org/10.1371/journal.pone.0159535 |
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