Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolism

In mammals, hepatic lipid catabolism is essential for the newborns to efficiently use milk fat as an energy source. However, it is unclear how this critical trait is acquired and regulated. We demonstrate that under the control of PPARα, the genes required for lipid catabolism are transcribed before...

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Detalles Bibliográficos
Autores principales: Rando, Gianpaolo, Tan, Chek Kun, Khaled, Nourhène, Montagner, Alexandra, Leuenberger, Nicolas, Bertrand-Michel, Justine, Paramalingam, Eeswari, Guillou, Hervé, Wahli, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963200/
https://www.ncbi.nlm.nih.gov/pubmed/27367842
http://dx.doi.org/10.7554/eLife.11853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963200/
https://www.ncbi.nlm.nih.gov/pubmed/27367842
http://dx.doi.org/10.7554/eLife.11853

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