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CD101 inhibits the expansion of colitogenic T cells

CD101 exerts negative-costimulatory effects in vitro, but its function in vivo remains poorly defined. CD101 is abundantly expressed on lymphoid and myeloid cells in intestinal tissues, but absent from naïve splenic T cells. Here, we assessed the impact of CD101 on the course of inflammatory bowel d...

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Detalles Bibliográficos
Autores principales: Schey, Regina, Dornhoff, Heike, Baier, Julia L.C., Purtak, Martin, Opoka, Robert, Koller, Anna Katharina, Atreya, Raya, Rau, Tilman T., Daniel, Christoph, Amann, Kerstin, Bogdan, Christian, Mattner, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963314/
https://www.ncbi.nlm.nih.gov/pubmed/26813346
http://dx.doi.org/10.1038/mi.2015.139