Polygenic risk score is associated with increased disease risk in 52 Finnish breast cancer families

The risk of developing breast cancer is increased in women with family history of breast cancer and particularly in families with multiple cases of breast or ovarian cancer. Nevertheless, many women with a positive family history never develop the disease. Polygenic risk scores (PRSs) based on the r...

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Detalles Bibliográficos
Autores principales: Muranen, Taru A., Mavaddat, Nasim, Khan, Sofia, Fagerholm, Rainer, Pelttari, Liisa, Lee, Andrew, Aittomäki, Kristiina, Blomqvist, Carl, Easton, Douglas F., Nevanlinna, Heli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963452/
https://www.ncbi.nlm.nih.gov/pubmed/27438779
http://dx.doi.org/10.1007/s10549-016-3897-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963452/
https://www.ncbi.nlm.nih.gov/pubmed/27438779
http://dx.doi.org/10.1007/s10549-016-3897-6

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