Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

The BubR1/Bub3 complex is an important regulator of chromosome segregation as it facilitates proper kinetochore–microtubule interactions and is also an essential component of the spindle assembly checkpoint (SAC). Whether BubR1/Bub3 localization to kinetochores in human cells stimulates SAC signalli...

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Detalles Bibliográficos
Autores principales: Zhang, Gang, Mendez, Blanca Lopez, Sedgwick, Garry G., Nilsson, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963475/
https://www.ncbi.nlm.nih.gov/pubmed/27457023
http://dx.doi.org/10.1038/ncomms12256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963475/
https://www.ncbi.nlm.nih.gov/pubmed/27457023
http://dx.doi.org/10.1038/ncomms12256

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