Asymmetric Inheritance of Aggregated Proteins and Age Reset in Yeast Are Regulated by Vac17-Dependent Vacuolar Functions

Age can be reset during mitosis in both yeast and stem cells to generate a young daughter cell from an aged and deteriorated one. This phenomenon requires asymmetry-generating genes (AGGs) that govern the asymmetrical inheritance of aggregated proteins. Using a genome-wide imaging screen to identify...

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Detalles Bibliográficos
Autores principales: Hill, Sandra Malmgren, Hao, Xinxin, Grönvall, Johan, Spikings-Nordby, Stephanie, Widlund, Per O., Amen, Triana, Jörhov, Anna, Josefson, Rebecca, Kaganovich, Daniel, Liu, Beidong, Nyström, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963537/
https://www.ncbi.nlm.nih.gov/pubmed/27373154
http://dx.doi.org/10.1016/j.celrep.2016.06.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963537/
https://www.ncbi.nlm.nih.gov/pubmed/27373154
http://dx.doi.org/10.1016/j.celrep.2016.06.016

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