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Transcriptomic Analysis of the Activity of a Novel Polymyxin against Staphylococcus aureus

Polymyxin B and colistin are exclusively active against Gram-negative pathogens and have been used in the clinic as a last-line therapy. In this study, we investigated the antimicrobial activity of a novel polymyxin, FADDI-019, against Staphylococcus aureus. MIC and time-kill assays were employed to...

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Detalles Bibliográficos
Autores principales: Zhao, Jinxin, Cheah, Soon-Ee, Roberts, Kade D., Nation, Roger L., Thompson, Philip E., Velkov, Tony, Du, Zongjun, Johnson, Matthew D., Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963539/
https://www.ncbi.nlm.nih.gov/pubmed/27471750
http://dx.doi.org/10.1128/mSphere.00119-16