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Circulating (CD3(−)CD19(+)CD20(−)IgD(−)CD27(high)CD38(high)) Plasmablasts: A Promising Cellular Biomarker for Immune Activity for Anti-PLA2R1 Related Membranous Nephropathy?

Membranous nephropathy (MN) is a kidney specific autoimmune disease mainly mediated by anti-phospholipase A2 receptor 1 autoantibody (PLA2R1 Ab). The adequate assessment of chimeric anti-CD20 monoclonal antibody, rituximab (RTX), efficacy is still needed to improve clinical outcome of patient with M...

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Detalles Bibliográficos
Autores principales: Pozdzik, Agnieszka, Beukinga, Ingrid, Gu-Trantien, Chunyan, Willard-Gallo, Karen, Nortier, Joëlle, Pradier, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963584/
https://www.ncbi.nlm.nih.gov/pubmed/27493452
http://dx.doi.org/10.1155/2016/7651024