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Downregulation of ADAMTS8 by DNA Hypermethylation in Gastric Cancer and Its Clinical Significance

A disintegrin and metallopeptidase with thrombospondin motif type 8 (ADAMTS8), a member of the ADAMTS family, was discovered as a novel angiogenesis inhibitor. We analyzed the expression and methylation of ADAMTS8 in primary gastric tumors and gastric cancer cell lines. We also examined the relation...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Zhang, Jiakui, Li, Xin, Zhang, Chundong, Zhang, Hongbin, Jin, Junzhe, Dai, Dongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963609/
https://www.ncbi.nlm.nih.gov/pubmed/27493958
http://dx.doi.org/10.1155/2016/5083841