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A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers

Aberrant WNT signaling underlies cancerous transformation and growth in many tissues, such as the colon, breast, liver, and others. Downregulation of the WNT pathway is a desired mode of development of targeted therapies against these cancers. Despite the urgent need, no WNT signaling-directed drugs...

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Detalles Bibliográficos
Autores principales: Ahmed, Kamal, Shaw, Holly V., Koval, Alexey, Katanaev, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963808/
https://www.ncbi.nlm.nih.gov/pubmed/27429001
http://dx.doi.org/10.3390/cancers8070066