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A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers
Aberrant WNT signaling underlies cancerous transformation and growth in many tissues, such as the colon, breast, liver, and others. Downregulation of the WNT pathway is a desired mode of development of targeted therapies against these cancers. Despite the urgent need, no WNT signaling-directed drugs...
Autores principales: | Ahmed, Kamal, Shaw, Holly V., Koval, Alexey, Katanaev, Vladimir L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963808/ https://www.ncbi.nlm.nih.gov/pubmed/27429001 http://dx.doi.org/10.3390/cancers8070066 |
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