Activation and Desensitization of Peripheral Muscle and Neuronal Nicotinic Acetylcholine Receptors by Selected, Naturally-Occurring Pyridine Alkaloids

Teratogenic alkaloids can cause developmental defects due to the inhibition of fetal movement that results from desensitization of fetal muscle-type nicotinic acetylcholine receptors (nAChRs). We investigated the ability of two known teratogens, the piperidinyl-pyridine anabasine and its 1,2-dehydro...

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Detalles Bibliográficos
Autores principales: Green, Benedict T., Lee, Stephen T., Welch, Kevin D., Cook, Daniel, Kem, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963837/
https://www.ncbi.nlm.nih.gov/pubmed/27384586
http://dx.doi.org/10.3390/toxins8070204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963837/
https://www.ncbi.nlm.nih.gov/pubmed/27384586
http://dx.doi.org/10.3390/toxins8070204

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