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Induction of artificial cancer stem cells from tongue cancer cells by defined reprogramming factors

BACKGROUND: The cancer stem cells (CSCs), a small subpopulation of cells in tumor are responsible for the tumor initiation, growth, recurrence and metastasis of cancer, as well as resistance of cancers to drugs or radiotherapy. CSCs are an important target for the development of novel strategies in...

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Detalles Bibliográficos
Autores principales: Harada, Koji, Ferdous, Tarannum, Cui, Dan, Kuramitsu, Yasuhiro, Matsumoto, Takuya, Ikeda, Eiji, Okano, Hideyuki, Ueyama, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963932/
https://www.ncbi.nlm.nih.gov/pubmed/27464948
http://dx.doi.org/10.1186/s12885-016-2416-9