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Integrative epigenomic analysis reveals unique epigenetic signatures involved in unipotency of mouse female germline stem cells

BACKGROUND: Germline stem cells play an essential role in establishing the fertility of an organism. Although extensively characterized, the regulatory mechanisms that govern the fundamental properties of mammalian female germline stem cells remain poorly understood. RESULTS: We generate genome-wide...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Li, Wu, Jun, Wang, Jian, Shen, Tingting, Li, Hua, Lu, Jun, Gu, Yunzhao, Kang, Yani, Wong, Chee-Hong, Ngan, Chew Yee, Shao, Zhifeng, Wu, Ji, Zhao, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963954/
https://www.ncbi.nlm.nih.gov/pubmed/27465593
http://dx.doi.org/10.1186/s13059-016-1023-z