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Recombinant Newcastle disease virus expressing P53 demonstrates promising antitumor efficiency in hepatoma model

BACKGROUND: Numerous studies have demonstrated that the NDV-mediated gene therapy is a promising new approach for treatment of cancers. P53 plays a vital role in tumor suppression and surveillance. Therefore, we hypothesize that a recombinant NDV expressing P53 would be an ideal agent for the hepato...

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Detalles Bibliográficos
Autores principales: An, Ying, Liu, Tianyan, He, Jinjiao, Wu, Hongsong, Chen, Rui, Liu, Yunye, Wu, Yunzhou, Bai, Yin, Guo, Xiaochen, Zheng, Qi, Liu, Chang, Yin, Jiechao, Li, Deshan, Ren, Guiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964062/
https://www.ncbi.nlm.nih.gov/pubmed/27465066
http://dx.doi.org/10.1186/s12929-016-0273-0