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Recombinant Newcastle disease virus expressing P53 demonstrates promising antitumor efficiency in hepatoma model
BACKGROUND: Numerous studies have demonstrated that the NDV-mediated gene therapy is a promising new approach for treatment of cancers. P53 plays a vital role in tumor suppression and surveillance. Therefore, we hypothesize that a recombinant NDV expressing P53 would be an ideal agent for the hepato...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964062/ https://www.ncbi.nlm.nih.gov/pubmed/27465066 http://dx.doi.org/10.1186/s12929-016-0273-0 |