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Immunoprofiling of leukemic stem cells CD34+/CD38−/CD123+ delineate FLT3/ITD-positive clones

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder presenting with accumulation of proliferating undifferentiated blasts. Xenograft transplantation studies have demonstrated a rare population of leukemia-initiating cells called leukemic stem cells (LSCs) capable of propagati...

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Detalles Bibliográficos
Autores principales: Al-Mawali, Adhra, Gillis, David, Lewis, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964068/
https://www.ncbi.nlm.nih.gov/pubmed/27465508
http://dx.doi.org/10.1186/s13045-016-0292-z