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Role of PKCtheta in macrophage-mediated immune response to Salmonella typhimurium infection in mice
BACKGROUND: The serine/threonine protein kinase C (PKC) theta has been firmly implicated in T cell-mediated immunity. Because its role in macrophages has remained undefined, we employed PKCtheta-deficient (PKCtheta(−/−)) mice in order to investigate if PKCtheta plays a role in macrophage-mediated im...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964075/ https://www.ncbi.nlm.nih.gov/pubmed/27465248 http://dx.doi.org/10.1186/s12964-016-0137-y |